Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL962740

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiproliferative activity against rat 9L cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Cell Type 9L
Confidence 1 — Organism
Curated By Autocuration

Target

9L (CHEMBL613105)
Type CELL-LINE
Organism Rattus norvegicus

Publication

Structure-activity relationship analysis of novel derivatives of narciclasine (an Amaryllidaceae isocarbostyril derivative) as potential anticancer agents.
Ingrassia L, Lefranc F, Dewelle J, Pottier L, Mathieu V, Spiegl-Kreinecker S, Sauvage S, El Yazidi M, Dehoux M, Berger W, Van Quaquebeke E, Kiss R.
J Med Chem (2009) 52 : 1100 -1114
PubMed 19199649 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.50 7.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL98745 NARCICLASINE 1 7.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL98745 NARCICLASINE IC50 = 32.0 nM 7.50