Assay Detail
Functional
CHEMBL962850
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Antitumor activity against mouse L1210 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | L1210 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antitumor activity evaluations of albumin-binding prodrugs of CC-1065 analog.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.59 | 9.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL480309 | — | — | 1 | 9.54 |
| CHEMBL14184 | HEXANOATE | — | 1 | 8.34 |
| CHEMBL367149 | DOCONEXENT | 3.0 | 1 | 7.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL480309 | — | IC50 | = | 0.29 | nM | 9.54 |
| CHEMBL14184 | HEXANOATE | IC50 | = | 4.6 | nM | 8.34 |
| CHEMBL367149 | DOCONEXENT | IC50 | = | 13.0 | nM | 7.89 |