Assay Detail
Binding
CHEMBL963183
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]granisetron form 5HT3 receptor in hybrid NG180-15 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | NG180-15 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel antagonists of serotonin-4 receptors: synthesis and biological evaluation of pyrrolothienopyrazines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.85 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL54720 | — | — | 1 | 8.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL54720 | — | IC50 | = | 1.413 | nM | 8.85 |