Assay Detail
Binding
CHEMBL963557
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]epibatidine from wild type Aplysia californica AchBP expressed in HEK293S cells by scintillation proximity assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Aplysia californica |
| Cell Type | HEK293S |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Nicotinic agonist binding site mapped by methionine- and tyrosine-scanning coupled with azidochloropyridinyl photoaffinity labeling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 8.44 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95904 | — | — | 1 | 8.77 |
| CHEMBL95352 | THIACLOPRID OLEFIN | — | 1 | 8.55 |
| CHEMBL55716 | AZIDOEPIBATIDINE | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95904 | — | Kd | = | 1.7 | nM | 8.77 |
| CHEMBL95352 | THIACLOPRID OLEFIN | Kd | = | 2.8 | nM | 8.55 |
| CHEMBL55716 | AZIDOEPIBATIDINE | Kd | = | 10.0 | nM | 8.00 |