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Assay Detail

CHEMBL963852

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine PDE2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Quinazolines as potent and highly selective PDE5 inhibitors as potential therapeutics for male erectile dysfunction.
Kim YH, Choi H, Lee J, Hwang IC, Moon SK, Kim SJ, Lee HW, Im DS, Lee SS, Ahn SK, Kim SW, Han CK, Yoon JH, Lee KJ, Choi NS.
Bioorg Med Chem Lett (2008) 18 : 6279 -6282
PubMed 18976905 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.98 4.98

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL521075 1 4.98

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL521075 IC50 = 10400.0 nM 4.98