Assay Detail
Functional
CHEMBL963924
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Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
6-Bicycloaryl substituted (S)- and (R)-5,6-dihydro-2H-pyran-2-ones: asymmetric synthesis, and anti-proliferative properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.57 | 4.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL470253 | — | — | 1 | 4.72 |
| CHEMBL464443 | GONIOTHALAMIN | — | 1 | 4.55 |
| CHEMBL451510 | — | — | 1 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL470253 | — | IC50 | = | 19000.0 | nM | 4.72 |
| CHEMBL464443 | GONIOTHALAMIN | IC50 | = | 28000.0 | nM | 4.55 |
| CHEMBL451510 | — | IC50 | = | 37000.0 | nM | 4.43 |