Assay Detail
Binding
CHEMBL964111
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Inhibition of HCV RNA dependent RNA polymerase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepatitis C virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Aryl diketoacids (ADK) selectively inhibit duplex DNA-unwinding activity of SARS coronavirus NTPase/helicase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.02 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL492768 | — | — | 1 | 6.02 |
| CHEMBL492770 | — | — | 1 | 6.02 |
| CHEMBL492771 | — | — | 1 | 6.02 |
| CHEMBL499444 | — | — | 1 | 6.02 |
| CHEMBL492772 | — | — | 1 | 6.02 |
| CHEMBL492571 | — | — | 1 | 6.02 |
| CHEMBL522710 | — | — | 1 | 6.02 |
| CHEMBL492769 | — | — | 1 | 6.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL492768 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL492770 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL492771 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL499444 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL492772 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL492571 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL522710 | — | IC50 | = | 960.0 | nM | 6.02 |
| CHEMBL492769 | — | IC50 | = | 960.0 | nM | 6.02 |