Assay Detail
Binding
CHEMBL964155
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Binding affinity to dopamine D4 receptor
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Discovery of novel non-peptidic beta-alanine piperazine amide derivatives and their optimization to achiral, easily accessible, potent and selective somatostatin sst1 receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.17 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL251541 | OBELIN | — | 1 | 8.30 |
| CHEMBL473763 | — | — | 1 | 6.90 |
| CHEMBL460542 | — | — | 1 | 6.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL251541 | OBELIN | Kd | = | 5.012 | nM | 8.30 |
| CHEMBL473763 | — | Kd | = | 125.89 | nM | 6.90 |
| CHEMBL460542 | — | Kd | = | 489.78 | nM | 6.31 |