Assay Detail
Binding
CHEMBL964245
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of acidic FGF-stimulated FGFR1 tyrosine autophosphorylation in mouse NIH/3T3 cells by immunoblotting
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.85 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89363 | — | — | 1 | 5.00 |
| CHEMBL315546 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89363 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL315546 | — | IC50 | = | 20000.0 | nM | 4.70 |