Assay Detail
Functional
CHEMBL965400
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic alkaloids and antibiotic nordammarane triterpenoids from the marine-derived fungus Aspergillus sydowi.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.37 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL488641 | 18-OXOTRYPROSTATIN A | — | 1 | 5.89 |
| CHEMBL487280 | — | — | 1 | 5.14 |
| CHEMBL488302 | SPIROTRYPROSTATIN B | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL488641 | 18-OXOTRYPROSTATIN A | IC50 | = | 1280.0 | nM | 5.89 |
| CHEMBL487280 | — | IC50 | = | 7310.0 | nM | 5.14 |
| CHEMBL488302 | SPIROTRYPROSTATIN B | IC50 | = | 8290.0 | nM | 5.08 |