Assay Detail
Functional
CHEMBL965929
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Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-8 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dibenzyl bromophenols with diverse dimerization patterns from the brown alga Leathesia nana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.28 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL253690 | — | — | 1 | 5.66 |
| CHEMBL482786 | — | — | 1 | 5.55 |
| CHEMBL252676 | — | — | 1 | 5.23 |
| CHEMBL491516 | — | — | 1 | 4.68 |
| CHEMBL482585 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL253690 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL482786 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL252676 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL491516 | — | IC50 | = | 20700.0 | nM | 4.68 |
| CHEMBL482585 | — | IC50 | > | 16800.0 | nM | - |