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Assay Detail

CHEMBL967076

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of GSK3
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-alpha and IL-6 inhibitors.
Bharate SB, Mahajan TR, Gole YR, Nambiar M, Matan TT, Kulkarni-Almeida A, Balachandran S, Junjappa H, Balakrishnan A, Vishwakarma RA.
Bioorg Med Chem (2008) 16 : 7167 -7176
PubMed 18625560 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.10 9.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL260417 1 9.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL260417 IC50 = 0.8 nM 9.10