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Assay Detail

CHEMBL967080

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antileishmanial activity against Leishmania amazonensis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania amazonensis
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania amazonensis (CHEMBL612877)
Type ORGANISM
Organism Leishmania amazonensis

Publication

Synthesis and evaluation of pyrazolo[3,4-b]pyridines and its structural analogues as TNF-alpha and IL-6 inhibitors.
Bharate SB, Mahajan TR, Gole YR, Nambiar M, Matan TT, Kulkarni-Almeida A, Balachandran S, Junjappa H, Balakrishnan A, Vishwakarma RA.
Bioorg Med Chem (2008) 16 : 7167 -7176
PubMed 18625560 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.92 6.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL363436 1 6.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL363436 IC50 = 120.0 nM 6.92