Assay Detail
Binding
CHEMBL967095
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Inhibition of prazosin uptake at transport-P transporter protein in mouse GT1-1 cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | GT1-1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Molecular features of the prazosin molecule required for activation of Transport-P.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.31 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL447719 | — | — | 1 | 6.72 |
| CHEMBL469254 | — | — | 1 | 6.34 |
| CHEMBL477341 | — | — | 1 | 5.35 |
| CHEMBL511930 | — | — | 1 | 5.28 |
| CHEMBL478179 | — | — | 1 | 5.27 |
| CHEMBL477551 | — | — | 1 | 4.10 |
| CHEMBL477552 | — | — | 1 | 4.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL447719 | — | IC50 | = | 190.0 | nM | 6.72 |
| CHEMBL469254 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL477341 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL511930 | — | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL478179 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL477551 | — | IC50 | = | 80000.0 | nM | 4.10 |
| CHEMBL477552 | — | IC50 | = | 81000.0 | nM | 4.09 |