Assay Detail
Functional
CHEMBL968045
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Agonist activity at GPR119 in hamster HIT-T15 cells stimulation of assessed as cAMP production
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cricetinae |
| Cell Type | HIT-T15 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.33 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL461384 | — | — | 1 | 8.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL461384 | — | EC50 | = | 4.7 | nM | 8.33 |