Assay Detail
Functional
CHEMBL968088
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Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Bel-7402 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Mono-, Bi-, and triphenanthrenes from the tubers of Cremastra appendiculata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.26 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL84 | TOPOTECAN | 4.0 | 1 | 5.92 |
| CHEMBL447029 | — | — | 1 | 5.09 |
| CHEMBL359501 | CIRRHOPETALANTHIN | — | 1 | 5.08 |
| CHEMBL498129 | — | — | 1 | 4.96 |
| CHEMBL498076 | — | — | 1 | - |
| CHEMBL447210 | FLAVANTHRININ | — | 1 | - |
| CHEMBL497448 | — | — | 1 | - |
| CHEMBL497447 | — | — | 1 | - |
| CHEMBL507982 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL84 | TOPOTECAN | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL447029 | — | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL359501 | CIRRHOPETALANTHIN | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL498129 | — | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL498076 | — | IC50 | > | 5000.0 | nM | - |
| CHEMBL447210 | FLAVANTHRININ | IC50 | > | 5000.0 | nM | - |
| CHEMBL497448 | — | IC50 | > | 5000.0 | nM | - |
| CHEMBL497447 | — | IC50 | > | 5000.0 | nM | - |
| CHEMBL507982 | — | IC50 | > | 5000.0 | nM | - |