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Assay Detail

CHEMBL969425

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Functional
Antifungal activity against Rhizoctonia solani assessed as inhibition of mycelial elongation after 48 hrs
ChEMBL ↗
79
Total Activities
40
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rhizoctonia solani
Confidence 1 — Organism
Curated By Autocuration

Target

Rhizoctonia solani (CHEMBL613272) ↗
Type ORGANISM
Organism Rhizoctonia solani

Publication

Synthesis, antifungal activity and CoMFA analysis of novel 1,2,4-triazolo[1,5-a]pyrimidine derivatives.
Chen Q, Zhu XL, Jiang LL, Liu ZM, Yang GF.
Eur J Med Chem (2008) 43 : 595 -603
PubMed 17618711 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 79 4.35 5.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL478124 — — 2 5.03
CHEMBL478544 — — 2 4.71
CHEMBL515967 — — 2 4.62
CHEMBL478501 — — 2 4.55
CHEMBL478914 — — 2 4.53
CHEMBL479218 — — 2 4.49
CHEMBL478546 — — 2 4.47
CHEMBL478123 — — 2 4.46
CHEMBL518755 — — 2 4.45
CHEMBL477509 — — 2 4.44
CHEMBL478553 — — 2 4.43
CHEMBL479166 — — 2 4.41
CHEMBL478122 — — 2 4.41
CHEMBL479219 — — 2 4.39
CHEMBL478167 — — 2 4.39
CHEMBL478992 — — 2 4.38
CHEMBL514063 — — 2 4.37
CHEMBL477302 — — 2 4.36
CHEMBL478500 — — 2 4.35
CHEMBL478293 — — 2 4.33
CHEMBL478915 — — 2 4.32
CHEMBL477272 — — 2 4.31
CHEMBL477274 — — 2 4.31
CHEMBL446549 — — 2 4.30
CHEMBL443102 — — 2 4.30
CHEMBL518740 — — 2 4.29
CHEMBL478104 — — 2 4.27
CHEMBL514549 — — 2 4.25
CHEMBL517521 — — 2 4.18
CHEMBL515182 — — 2 4.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL478124 — EC50 = 9332.54 nM 5.03
CHEMBL478544 — EC50 = 19498.45 nM 4.71
CHEMBL515967 — EC50 = 23988.33 nM 4.62
CHEMBL478501 — EC50 = 28183.83 nM 4.55
CHEMBL478914 — EC50 = 29512.09 nM 4.53
CHEMBL479218 — EC50 = 32359.37 nM 4.49
CHEMBL478546 — EC50 = 33884.42 nM 4.47
CHEMBL478123 — EC50 = 34673.69 nM 4.46
CHEMBL518755 — EC50 = 35481.34 nM 4.45
CHEMBL477509 — EC50 = 36307.81 nM 4.44
CHEMBL478553 — EC50 = 37153.52 nM 4.43
CHEMBL478122 — EC50 = 38904.51 nM 4.41
CHEMBL479166 — EC50 = 38904.51 nM 4.41
CHEMBL479219 — EC50 = 40738.03 nM 4.39
CHEMBL478167 — EC50 = 40738.03 nM 4.39
CHEMBL478992 — EC50 = 41686.94 nM 4.38
CHEMBL514063 — EC50 = 42657.95 nM 4.37
CHEMBL477302 — EC50 = 43651.58 nM 4.36
CHEMBL478500 — EC50 = 44668.36 nM 4.35
CHEMBL478293 — EC50 = 46773.51 nM 4.33
CHEMBL478915 — EC50 = 47863.01 nM 4.32
CHEMBL477272 — EC50 = 48977.88 nM 4.31
CHEMBL477274 — EC50 = 48977.88 nM 4.31
CHEMBL446549 — EC50 = 50118.72 nM 4.30
CHEMBL443102 — EC50 = 50118.72 nM 4.30
CHEMBL518740 — EC50 = 51286.14 nM 4.29
CHEMBL478104 — EC50 = 53703.18 nM 4.27
CHEMBL514549 — EC50 = 56234.13 nM 4.25
CHEMBL517521 — EC50 = 66069.34 nM 4.18
CHEMBL515182 — EC50 = 72443.6 nM 4.14
CHEMBL479221 — EC50 = 74131.02 nM 4.13
CHEMBL517668 — EC50 = 74131.02 nM 4.13
CHEMBL514862 — EC50 = 81283.05 nM 4.09
CHEMBL477097 — EC50 = 83176.38 nM 4.08
CHEMBL477273 — EC50 = 83176.38 nM 4.08
CHEMBL478337 — EC50 = 97723.72 nM 4.01
CHEMBL446549 — EC50 = 15.58 ug.mL-1 -
CHEMBL478124 — EC50 = 3.34 ug.mL-1 -
CHEMBL478123 — EC50 = 14.2 ug.mL-1 -
CHEMBL478122 — EC50 = 16.97 ug.mL-1 -
CHEMBL478992 — EC50 = 17.94 ug.mL-1 -
CHEMBL478915 — EC50 = 19.64 ug.mL-1 -
CHEMBL478914 — EC50 = 12.54 ug.mL-1 -
CHEMBL477509 — EC50 = 15.87 ug.mL-1 -
CHEMBL515967 — EC50 = 9.97 ug.mL-1 -
CHEMBL514063 — EC50 = 16.38 ug.mL-1 -
CHEMBL478545 — EC50 = 102329.3 nM -
CHEMBL479166 — EC50 = 15.8 ug.mL-1 -
CHEMBL514393 — EC50 = 138038.43 nM -
CHEMBL514223 — EC50 = 151356.12 nM -