Assay Detail
Functional
CHEMBL969449
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Antiproliferative activity against human KB cells after 72 hrs by MTS test
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.49 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL515155 | ISOINDIGO | — | 1 | 5.80 |
| CHEMBL454578 | — | — | 1 | 5.80 |
| CHEMBL502907 | — | — | 1 | 4.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL515155 | ISOINDIGO | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL454578 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL502907 | — | IC50 | = | 13900.0 | nM | 4.86 |