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Assay Detail

CHEMBL969706

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HDAC
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Design, synthesis and biological evaluation of novel compounds with conjugated structure as anti-tumor agents.
Su H, Nebbioso A, Carafa V, Chen Y, Yang B, Altucci L, You Q.
Bioorg Med Chem (2008) 16 : 7992 -8002
PubMed 18701301 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.78 7.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL314389 OXAMFLATIN 1 7.80
CHEMBL159249 1 5.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL314389 OXAMFLATIN IC50 = 15.7 nM 7.80
CHEMBL159249 IC50 = 1800.0 nM 5.75