Assay Detail
Binding
CHEMBL969896
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Inhibition of bovine 5LOX
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Investigations concerning the COX/5-LOX inhibiting and hydroxyl radical scavenging potencies of novel 4,5-diaryl isoselenazoles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.95 | 6.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL300982 | LICOFELONE | 2.0 | 1 | 6.75 |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | — | 1 | 6.00 |
| CHEMBL452744 | — | — | 1 | 5.10 |
| CHEMBL134342 | THIOCTIC ACID | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL300982 | LICOFELONE | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL452744 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL134342 | THIOCTIC ACID | IC50 | - | — | - |