Assay Detail
Functional
CHEMBL970475
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Antiviral activity against Influenza A virus (A/Singapore/1/1957 (H2N2)) assessed viral plaque reduction
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus (A/Singapore/1/1957(H2N2)) |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and in vivo influenza virus-inhibitory effect of ester prodrug of 4-guanidino-7-O-methyl-Neu5Ac2en.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 9.24 | 9.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL466246 | LANINAMIVIR | 2.0 | 1 | 9.37 |
| CHEMBL222813 | ZANAMIVIR | 4.0 | 1 | 9.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL466246 | LANINAMIVIR | IC50 | = | 0.43 | nM | 9.37 |
| CHEMBL222813 | ZANAMIVIR | IC50 | = | 0.79 | nM | 9.10 |