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Assay Detail

CHEMBL970973

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK4
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Cyclin-dependent kinase 4 (CHEMBL331)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets.
McArdle BM, Campitelli MR, Quinn RJ.
J Nat Prod (2006) 69 : 14 -17
PubMed 16441060 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.46 6.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL258765 FASCAPLYSIN CHLORIDE 1 6.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL258765 FASCAPLYSIN CHLORIDE IC50 = 350.0 nM 6.46