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Assay Detail

CHEMBL970979

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CK2
7
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A common protein fold topology shared by flavonoid biosynthetic enzymes and therapeutic targets.
McArdle BM, Campitelli MR, Quinn RJ.
J Nat Prod (2006) 69 : 14 -17
PubMed 16441060 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 5 5.97 6.46
Ki 2 6.07 6.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL31574 FISETIN 2.0 1 6.46
CHEMBL50 QUERCETIN 3.0 1 6.26
CHEMBL164 MYRICETIN 2 6.22
CHEMBL28 APIGENIN 1 6.10
CHEMBL165 RESVERATROL 3.0 2 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL31574 FISETIN IC50 = 350.0 nM 6.46
CHEMBL50 QUERCETIN IC50 = 550.0 nM 6.26
CHEMBL164 MYRICETIN Ki = 600.0 nM 6.22
CHEMBL28 APIGENIN IC50 = 800.0 nM 6.10
CHEMBL164 MYRICETIN IC50 = 920.0 nM 6.04
CHEMBL165 RESVERATROL Ki = 1200.0 nM 5.92
CHEMBL165 RESVERATROL IC50 = 10000.0 nM 5.00