Assay Detail
Binding
CHEMBL971577
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Inhibition of IGFR
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of potent c-Met inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 6.67 | 7.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL453737 | — | — | 1 | 7.66 |
| CHEMBL447602 | — | — | 1 | 7.29 |
| CHEMBL461831 | — | — | 1 | 7.16 |
| CHEMBL444560 | — | — | 1 | 6.07 |
| CHEMBL461648 | — | — | 1 | 5.99 |
| CHEMBL505896 | — | — | 1 | 5.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL453737 | — | Ki | = | 22.0 | nM | 7.66 |
| CHEMBL447602 | — | Ki | = | 51.0 | nM | 7.29 |
| CHEMBL461831 | — | Ki | = | 70.0 | nM | 7.16 |
| CHEMBL444560 | — | Ki | = | 860.0 | nM | 6.07 |
| CHEMBL461648 | — | Ki | = | 1030.0 | nM | 5.99 |
| CHEMBL505896 | — | Ki | = | 1450.0 | nM | 5.84 |