Assay Detail

CHEMBL971881

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Functional

Cytotoxicity against human HT-29 cells after 72 hrs

ChEMBL ↗

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Target

HT-29 (CHEMBL384) ↗

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Primary target HT-29

CHEMBL384

Anchored from Assay target.

Protein identity HT-29

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HT-29
Confidence	1 — Organism
Curated By	Autocuration

Target

HT-29 (CHEMBL384) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Bioactive depsides and anthocyanins from jaboticaba (Myrciaria cauliflora).

Reynertson KA, Wallace AM, Adachi S, Gil RR, Yang H, Basile MJ, D'Armiento J, Weinstein IB, Kennelly EJ.
J Nat Prod (2006) 69 : 1228 -1230
PubMed 16933884 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	4.10	4.19

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL495849	JABOTICABIN	—	1	4.19
CHEMBL257839	KUROMANIN	—	1	4.00

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL495849	JABOTICABIN	IC50	=	65000.0	nM	4.19
CHEMBL257839	KUROMANIN	IC50	=	100000.0	nM	4.00