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Assay Detail

CHEMBL972065

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]CCK-8 from CCK2 receptor in human FGS7 Jurkat cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type Jurkat
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Gastrin/cholecystokinin type B receptor (CHEMBL298)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro.
Gafner S, Dietz BM, McPhail KL, Scott IM, Glinski JA, Russell FE, McCollom MM, Budzinski JW, Foster BC, Bergeron C, Rhyu MR, Bolton JL.
J Nat Prod (2006) 69 : 432 -435
PubMed 16562853 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 10.03 10.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1121 SINCALIDE 4.0 1 10.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1121 SINCALIDE EC50 = 0.093 nM 10.03