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Assay Detail

CHEMBL972079

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against MLF cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Mus musculus
Cell Type MLF
Confidence 1 — Organism
Curated By Autocuration

Target

MLF (CHEMBL613547)
Type CELL-LINE
Organism Mus musculus

Publication

Synthesis and biological evaluation of analogues of cryptolepine, an alkaloid isolated from the Suriname rainforest.
Yang SW, Abdel-Kader M, Malone S, Werkhoven MC, Wisse JH, Bursuker I, Neddermann K, Fairchild C, Raventos-Suarez C, Menendez AT, Lane K, Kingston DG.
J Nat Prod (1999) 62 : 976 -983
PubMed 10425120 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.31 5.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL172017 1 5.31
CHEMBL491341 1 5.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL172017 IC50 = 4900.0 nM 5.31
CHEMBL491341 IC50 = 4900.0 nM 5.31