Assay Detail
Binding
CHEMBL972292
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SARS coronavirus 3CL proteinase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome-related coronavirus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Replicase polyprotein 1a (CHEMBL3927) ↗| Type | SINGLE PROTEIN |
| Organism | Severe acute respiratory syndrome-related coronavirus |
Publication
Heteroaromatic ester inhibitors of hepatitis A virus 3C proteinase: Evaluation of mode of action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.80 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL222234 | — | — | 1 | 7.30 |
| CHEMBL468553 | — | — | 1 | 6.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL222234 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL468553 | — | IC50 | = | 500.0 | nM | 6.30 |