Assay Detail
Binding
CHEMBL972368
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Inhibition of recombinant wild-type MAOA from human liver expressed in Pichia pastoris
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of monoamine oxidase by (E)-styrylisatin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.30 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL466872 | — | — | 1 | 6.11 |
| CHEMBL506301 | — | — | 1 | 5.66 |
| CHEMBL447307 | — | — | 1 | 5.25 |
| CHEMBL326294 | ISATIN | — | 1 | 4.82 |
| CHEMBL450239 | (E)-6-STYRYLISATIN | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL466872 | — | Ki | = | 780.0 | nM | 6.11 |
| CHEMBL506301 | — | Ki | = | 2200.0 | nM | 5.66 |
| CHEMBL447307 | — | Ki | = | 5600.0 | nM | 5.25 |
| CHEMBL326294 | ISATIN | Ki | = | 15000.0 | nM | 4.82 |
| CHEMBL450239 | (E)-6-STYRYLISATIN | Ki | = | 22000.0 | nM | 4.66 |