Assay Detail
Binding
CHEMBL972369
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Inhibition of recombinant wild-type MAOB from human liver expressed in Pichia pastoris
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of monoamine oxidase by (E)-styrylisatin analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.24 | 7.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL26138 | — | — | 1 | 7.07 |
| CHEMBL466872 | — | — | 1 | 6.51 |
| CHEMBL450239 | (E)-6-STYRYLISATIN | — | 1 | 6.25 |
| CHEMBL506301 | — | — | 1 | 6.22 |
| CHEMBL447307 | — | — | 1 | 5.85 |
| CHEMBL326294 | ISATIN | — | 1 | 5.52 |
| CHEMBL113 | CAFFEINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL26138 | — | Ki | = | 86.0 | nM | 7.07 |
| CHEMBL466872 | — | Ki | = | 310.0 | nM | 6.51 |
| CHEMBL450239 | (E)-6-STYRYLISATIN | Ki | = | 560.0 | nM | 6.25 |
| CHEMBL506301 | — | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL447307 | — | Ki | = | 1400.0 | nM | 5.85 |
| CHEMBL326294 | ISATIN | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL113 | CAFFEINE | Ki | = | 3600000.0 | nM | - |