Assay Detail
Functional
CHEMBL972823
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Cytotoxicity against human U251 cells after 48 hrs by SRB assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-251 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic cis-fused bicyclic sesquiterpenoids from Jatropha neopauciflora.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.07 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.50 |
| CHEMBL453161 | — | — | 1 | 4.39 |
| CHEMBL462795 | CALENDULADIOL | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL453161 | — | IC50 | = | 41040.0 | nM | 4.39 |
| CHEMBL462795 | CALENDULADIOL | IC50 | = | 48440.0 | nM | 4.32 |