Assay Detail
Binding
CHEMBL972983
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX2
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Bioactive dammarane triterpenes from the mangrove plant Bruguiera gymnorrhiza.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 2 | - | - |
| IC50 | 1 | 6.43 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL504631 | BRUGUIERIN A | — | 1 | 6.43 |
| CHEMBL447269 | BRUGUIERIN B | — | 1 | - |
| CHEMBL503931 | BRUGUIERIN C | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL504631 | BRUGUIERIN A | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL447269 | BRUGUIERIN B | Activity | - | — | - | |
| CHEMBL503931 | BRUGUIERIN C | Activity | - | — | - |