Assay Detail
Functional
CHEMBL972985
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Cytotoxicity against human HEP2 cells after 72 hrs by [3H]thymidine incorporation assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEp-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic activities of hypocretenolides from Leontodon hispidus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.09 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL503318 | — | — | 1 | 6.22 |
| CHEMBL338474 | HELENALIN | — | 1 | 6.10 |
| CHEMBL365306 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL503318 | — | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL338474 | HELENALIN | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL365306 | — | IC50 | = | 1100.0 | nM | 5.96 |