Assay Detail
Binding
CHEMBL973087
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Src
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Target
Proto-oncogene tyrosine-protein kinase Src (CHEMBL267) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.61 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL217092 | SARACATINIB | 3.0 | 1 | 8.52 |
| CHEMBL189584 | PD-173074 | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL217092 | SARACATINIB | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL189584 | PD-173074 | IC50 | = | 20000.0 | nM | 4.70 |