Assay Detail
Binding
CHEMBL973768
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HIV1 protease
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Anti-HIV-1 protease triterpenoid saponins from the seeds of Aesculus chinensis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.38 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507233 | ESCIN IA | — | 1 | 4.46 |
| CHEMBL505939 | ESCIN IB | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507233 | ESCIN IA | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL505939 | ESCIN IB | IC50 | = | 50000.0 | nM | 4.30 |