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Assay Detail

CHEMBL974047

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration against cap-dependent endonuclease activity of influenza A/PR/8/34 RNP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Confidence 9 — Direct single protein target
Curated By Expert

Target

Polymerase acidic protein (CHEMBL1169598)
Type SINGLE PROTEIN
Organism Influenza A virus (A/Puerto Rico/8/1934(H1N1))

Publication

Tetramic and tetronic acids: an update on new derivatives and biological aspects.
Schobert R, Schlenk A.
Bioorg Med Chem (2008) 16 : 4203 -4221
PubMed 18334299 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL16525 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL16525 IC50 = 3000.0 nM 5.52