Assay Detail

CHEMBL974402

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Binding

Inhibition of rat liver CK2 catalytic activity

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Rattus norvegicus
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid.

Sekiguchi Y, Nakaniwa T, Kinoshita T, Nakanishi I, Kitaura K, Hirasawa A, Tsujimoto G, Tada T.
Bioorg Med Chem Lett (2009) 19 : 2920 -2923
PubMed 19414254 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	7.40	7.40

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL6246	ELLAGIC ACID	2.0	1	7.40

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL6246	ELLAGIC ACID	IC50	=	40.0	nM	7.40