Assay Detail
Functional
CHEMBL974675
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Cytotoxicity against human HT29 cells after 6 days by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic dihydroagarofuranoid sesquiterpenes from the stem of Microtropis fokienensis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.17 | 7.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL504778 | FOKIENAGAROFURAN A | — | 1 | 7.27 |
| CHEMBL487597 | FOKIENAGAROFURAN D | — | 1 | 7.24 |
| CHEMBL509964 | — | — | 1 | 7.15 |
| CHEMBL1237054 | PLICAMYCIN | 4.0 | 1 | 7.10 |
| CHEMBL509571 | — | — | 1 | 7.09 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL504778 | FOKIENAGAROFURAN A | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL487597 | FOKIENAGAROFURAN D | IC50 | = | 58.0 | nM | 7.24 |
| CHEMBL509964 | — | IC50 | = | 71.0 | nM | 7.15 |
| CHEMBL1237054 | PLICAMYCIN | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL509571 | — | IC50 | = | 82.0 | nM | 7.09 |