Assay Detail
Binding
CHEMBL975662
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of electric eel AChE by Ellman's assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Electrophorus electricus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Taspine: bioactivity-guided isolation and molecular ligand-target insight of a potent acetylcholinesterase inhibitor from Magnolia x soulangiana.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.21 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL95 | TACRINE | 4.0 | 1 | 6.66 |
| CHEMBL470867 | TASPINE | — | 1 | 6.48 |
| CHEMBL659 | GALANTAMINE | 4.0 | 1 | 5.50 |
| CHEMBL469423 | (-)-ASIMILOBINE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL95 | TACRINE | IC50 | = | 220.0 | nM | 6.66 |
| CHEMBL470867 | TASPINE | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL659 | GALANTAMINE | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL469423 | (-)-ASIMILOBINE | IC50 | > | 100000.0 | nM | - |