Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL976464

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HCV RNA-dependent RNA polymerase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepatitis C virus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Effects of the aryl linker and the aromatic substituent on the anti-HCV activities of aryl diketoacid (ADK) analogues.
Kim J, Kim KS, Lee HS, Park KS, Park SY, Kang SY, Lee SJ, Park HS, Kim DE, Chong Y.
Bioorg Med Chem Lett (2008) 18 : 4661 -4665
PubMed 18644717 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.94 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL492770 1 5.10
CHEMBL492571 1 4.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL492770 IC50 = 8000.0 nM 5.10
CHEMBL492571 IC50 = 17000.0 nM 4.77