Assay Detail
Functional
CHEMBL976684
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Cytotoxicity against human SKOV3 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic hypothemycin analogues from Hypomyces subiculosus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.29 | 7.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL518087 | — | — | 1 | 7.42 |
| CHEMBL471474 | HYPOTHEMYCIN | — | 1 | 7.16 |
| CHEMBL516861 | — | — | 1 | - |
| CHEMBL471473 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL518087 | — | IC50 | = | 38.0 | nM | 7.42 |
| CHEMBL471474 | HYPOTHEMYCIN | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL516861 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL471473 | — | IC50 | > | 100000.0 | nM | - |