Assay Detail
Functional
CHEMBL976778
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Inhibition of mouse Hepa-1c1c7 cells assessed as cell viability
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Hepa-1c1c7 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Quinone reductase induction as a biomarker for cancer chemoprevention.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.96 | 5.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL48802 | SULFORAPHANE | 3.0 | 1 | 5.20 |
| CHEMBL129795 | ISOLIQUIRITIGENIN | — | 1 | 4.71 |
| CHEMBL294099 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL48802 | SULFORAPHANE | IC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL129795 | ISOLIQUIRITIGENIN | IC50 | = | 19600.0 | nM | 4.71 |
| CHEMBL294099 | — | IC50 | > | 62500.0 | nM | - |