Assay Detail

CHEMBL976789

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Inhibition of mouse Hepa-1c1c7 TAOc1Bprc1 mutant cells assessed as cell viability

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Mus musculus
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Quinone reductase induction as a biomarker for cancer chemoprevention.

Cuendet M, Oteham CP, Moon RC, Pezzuto JM.
J Nat Prod (2006) 69 : 460 -463
PubMed 16562858 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	3	4.95	5.23

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL48802	SULFORAPHANE	3.0	1	5.23
CHEMBL129795	ISOLIQUIRITIGENIN	—	1	4.66
CHEMBL294099	—	—	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL48802	SULFORAPHANE	IC50	=	5900.0	nM	5.23
CHEMBL129795	ISOLIQUIRITIGENIN	IC50	=	22000.0	nM	4.66
CHEMBL294099	—	IC50	>	62500.0	nM	-