Assay Detail
Binding
CHEMBL977663
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells by liquid scintillation counting
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Serotonergic activity-guided phytochemical investigation of the roots of Angelica sinensis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.32 | 4.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL481245 | — | — | 1 | 4.32 |
| CHEMBL479891 | — | — | 1 | - |
| CHEMBL69018 | FALCARINDIOL | — | 1 | - |
| CHEMBL490698 | — | — | 1 | - |
| CHEMBL249592 | Z-butylidenephthalide | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL481245 | — | IC50 | = | 47600.0 | nM | 4.32 |
| CHEMBL479891 | — | IC50 | > | 150000.0 | nM | - |
| CHEMBL69018 | FALCARINDIOL | IC50 | = | 117500.0 | nM | - |
| CHEMBL490698 | — | IC50 | = | 118100.0 | nM | - |
| CHEMBL249592 | Z-butylidenephthalide | IC50 | = | 126600.0 | nM | - |