Assay Detail
Binding
CHEMBL977794
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Displacement of [125I]MCP1 from CCR2 expressed in CHOK1 cells
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO-K1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.60 | 9.60 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL41275 | — | — | 2 | 9.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL41275 | — | IC50 | = | 0.25 | nM | 9.60 |
| CHEMBL41275 | — | Inhibition | = | 91.3 | % | - |