Assay Detail
Functional
CHEMBL977835
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Antimalarial activity against Plasmodium falciparum W2 by [3H]hypoxanthine uptake
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antimalarial compounds from Grewia bilamellata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.17 | 6.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | 4.0 | 1 | 6.57 |
| CHEMBL479692 | GREWIN | — | 1 | 5.26 |
| CHEMBL201515 | MASLINIC ACID | — | 1 | 5.07 |
| CHEMBL479693 | NITIDANIN | — | 1 | 4.74 |
| CHEMBL481837 | — | — | 1 | 4.72 |
| CHEMBL477855 | — | — | 1 | 4.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL76 | CHLOROQUINE | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL479692 | GREWIN | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL201515 | MASLINIC ACID | IC50 | = | 8600.0 | nM | 5.07 |
| CHEMBL479693 | NITIDANIN | IC50 | = | 18400.0 | nM | 4.74 |
| CHEMBL481837 | — | IC50 | = | 19100.0 | nM | 4.72 |
| CHEMBL477855 | — | IC50 | = | 23000.0 | nM | 4.64 |