Assay Detail
Binding
CHEMBL978161
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of COX2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.50 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL111562 | — | — | 1 | 8.70 |
| CHEMBL108201 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL111562 | — | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL108201 | — | IC50 | = | 5.0 | nM | 8.30 |