Assay Detail
Binding
CHEMBL978330
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Inhibition of human recombinant COX2
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Nitrogen-containing phorbol esters from Croton ciliatoglandulifer and their effects on cyclooxygenases-1 and -2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.56 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL500387 | — | — | 1 | 5.66 |
| CHEMBL503071 | — | — | 1 | 5.66 |
| CHEMBL502799 | — | — | 1 | 5.66 |
| CHEMBL6 | INDOMETHACIN | 4.0 | 1 | 5.24 |
| CHEMBL525601 | — | — | 1 | - |
| CHEMBL526931 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL500387 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL503071 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL502799 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL6 | INDOMETHACIN | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL525601 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL526931 | — | IC50 | > | 100000.0 | nM | - |