Assay Detail
Functional
CHEMBL978892
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Cytotoxicity against human SKOV3 cells by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SK-OV-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of potent antitumor and antiviral benzofuran derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 10.16 | 10.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL468747 | — | — | 1 | 10.59 |
| CHEMBL513819 | — | — | 1 | 10.59 |
| CHEMBL466114 | — | — | 1 | 10.59 |
| CHEMBL466908 | — | — | 1 | 10.56 |
| CHEMBL3143911 | — | — | 1 | 10.55 |
| CHEMBL466909 | — | — | 1 | 10.55 |
| CHEMBL449897 | — | — | 1 | 10.49 |
| CHEMBL468539 | — | — | 1 | 10.48 |
| CHEMBL466907 | — | — | 1 | 10.48 |
| CHEMBL511905 | — | — | 1 | 8.48 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 8.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL468747 | — | IC50 | = | 0.0255 | nM | 10.59 |
| CHEMBL513819 | — | IC50 | = | 0.0255 | nM | 10.59 |
| CHEMBL466114 | — | IC50 | = | 0.0255 | nM | 10.59 |
| CHEMBL466908 | — | IC50 | = | 0.0277 | nM | 10.56 |
| CHEMBL3143911 | — | IC50 | = | 0.0284 | nM | 10.55 |
| CHEMBL466909 | — | IC50 | = | 0.0284 | nM | 10.55 |
| CHEMBL449897 | — | IC50 | = | 0.032 | nM | 10.49 |
| CHEMBL468539 | — | IC50 | = | 0.0328 | nM | 10.48 |
| CHEMBL466907 | — | IC50 | = | 0.0328 | nM | 10.48 |
| CHEMBL511905 | — | IC50 | = | 3.28 | nM | 8.48 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 4.16 | nM | 8.38 |