Assay Detail
Functional
CHEMBL978897
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Cytotoxicity against human U937 cells by MTT assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-937 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of potent antitumor and antiviral benzofuran derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 10.33 | 10.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL449897 | — | — | 1 | 10.58 |
| CHEMBL466907 | — | — | 1 | 10.57 |
| CHEMBL466909 | — | — | 1 | 10.55 |
| CHEMBL511905 | — | — | 1 | 10.55 |
| CHEMBL468539 | — | — | 1 | 10.54 |
| CHEMBL3143911 | — | — | 1 | 10.53 |
| CHEMBL466908 | — | — | 1 | 10.53 |
| CHEMBL513819 | — | — | 1 | 10.52 |
| CHEMBL468747 | — | — | 1 | 10.48 |
| CHEMBL466114 | — | — | 1 | 10.48 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 8.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL449897 | — | IC50 | = | 0.0263 | nM | 10.58 |
| CHEMBL466907 | — | IC50 | = | 0.0272 | nM | 10.57 |
| CHEMBL466909 | — | IC50 | = | 0.0284 | nM | 10.55 |
| CHEMBL511905 | — | IC50 | = | 0.0284 | nM | 10.55 |
| CHEMBL468539 | — | IC50 | = | 0.0291 | nM | 10.54 |
| CHEMBL3143911 | — | IC50 | = | 0.0298 | nM | 10.53 |
| CHEMBL466908 | — | IC50 | = | 0.0298 | nM | 10.53 |
| CHEMBL513819 | — | IC50 | = | 0.0301 | nM | 10.52 |
| CHEMBL468747 | — | IC50 | = | 0.0333 | nM | 10.48 |
| CHEMBL466114 | — | IC50 | = | 0.0329 | nM | 10.48 |
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 4.45 | nM | 8.35 |